5-Bromo-3-chloro-2-(methoxycarbonyl)pyridine, Methyl 5-bromo-3-chloropicolinate - Names and Identifiers
5-Bromo-3-chloro-2-(methoxycarbonyl)pyridine, Methyl 5-bromo-3-chloropicolinate - Physico-chemical Properties
Molecular Formula | C7H5BrClNO2
|
Molar Mass | 250.48 |
Density | 1.684 |
Boling Point | 311℃ |
Flash Point | 142℃ |
pKa | -3.26±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
5-Bromo-3-chloro-2-(methoxycarbonyl)pyridine, Methyl 5-bromo-3-chloropicolinate - Introduction
Methyl 5-bromo-3-chloro-2-pyridinecarboxylate is an organic compound whose chemical formula is C8H6BrClNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
Methyl 5-bromo-3-chloro-2-pyridinecarboxylate is a colorless or pale yellow liquid. It has a low boiling point and melting point and is soluble in many organic solvents, such as ethanol, ether and chloroform. It is relatively stable at room temperature, but may decompose when exposed to high temperatures, light or strong oxidants.
Use:
5-Bromo-3-chloro-2-pyridinecarboxylic acid methyl ester has certain application value in the chemical industry. It can be used as an intermediate in organic synthesis for the synthesis of other compounds, such as pesticides, pharmaceuticals and dye intermediates. It can also be used as an additive for organic synthesis reagents and catalysts.
Preparation Method:
The preparation method of methyl 5-bromo-3-chloro-2-pyridinecarboxylate can be achieved by bromination and chlorination of methyl 2-pyridinecarboxylate. First, methyl 2-picolinate is reacted with bromine and chlorine under appropriate conditions to give the desired product.
Safety Information:
5-Bromo-3-chloro-2-pyridinecarboxylic acid methyl ester needs to be safe during operation. It is an irritating compound that can cause irritation to the eyes, skin and respiratory system. Avoid inhaling gases, vapors, mist or dust when in contact, and avoid wetting the skin. Wear appropriate personal protective equipment when handling or operating, including safety glasses, protective gloves and protective clothing. If necessary, operate in a well-ventilated place and follow relevant safety operating procedures. After treatment, it should be thoroughly cleaned to avoid pollution to the environment. If you accidentally touch or take it by mistake, you should seek medical help immediately.
Last Update:2024-04-09 21:01:54